PPAR-Gamma Agonist Pioglitazone Reduced CD68+ but Not CD163+ Macrophage Dermal Infiltration in Obese Psoriatic Patients

<div>Immunohistochemical detection of CD68+ cells in psoriatic plaque biopsy specimens. (a) CD68+ cells (arrows) in the infiltrate and the reticular layer of the dermis before treatment. (b) Single CD68+ cells (arrow) after the treatment with 30 mg pioglitazone. Contrasting: Mayer’s haemalaun, mg, ×400. Scale bars, 0.2 <i>μ</i>m. (c) CD68+ cells reduced significantly (Wilcoxon method).</div>

PPAR Research

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Figure 3

Figure 3: PPAR-Gamma Agonist Pioglitazone Reduced CD68+ but Not CD163+ Macrophage Dermal Infiltration in Obese Psoriatic Patients 