To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations

<div>Sequence alignment of PPAR<i>α</i> (PDB ID: 3VI8), PPAR<i>β</i> (PDB ID: 3TKM), and PPAR<i>γ</i> (PDB ID: 2PRG): 202 (alpha), 174 (beta/delta), and 238 (gamma). The sequences were aligned using PPAR<i>γ</i> as a reference, and each residue that differs is colored based on side-chain chemistry. See Materials and Methods for reference to colors.</div>

PPAR Research

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Figure 1

Figure 1: To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations 

Figure 1 | To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations 