Comparative Study of PPARγ Targets in Human Extravillous and Villous Cytotrophoblasts

Figure 4

GO and pathway terms associated with DEGs that were upregulated in RT-EVCTs and RT-VCTs. These DEGs were submitted separately to ClueGO by their cell type of origin with the default parameters. GO and pathway enrichment were set up for analysis. Upregulated DEGs were classified by three ways: by their GO biological process, GO molecular function, and GO cellular component. The KEGG and Reactome databases were consulted to determine pathway enrichment. All additional enrichment terms (not shown above) can be found in supplementary materials (Tables S1-S8). DEGs: differentially expressed genes; RT-EVCTs: rosiglitazone-treated extravillous cytotrophoblasts; RT-VCTs: rosiglitazone-treated villous cytotrophoblasts; GO: gene ontology; KEGG: Kyoto encyclopedia of genes and genomes.