Research Article

Fenofibrate Exerts Antitumor Effects in Colon Cancer via Regulation of DNMT1 and CDKN2A

Figure 7

Fenofibrate modulated cell cycle via CDKN2A/RB/E2F transcript cascade. (a) Cell cycle distribution was examined using flow cytometry. (b) The mRNA expression of RB, E2F1, CDK4, CDK6, and Cyclin D1 was measured using qRT-PCR. Data was presented as (, , ). (c) Western blot analysis of DNMT1, RB, pRB, E2F1, PPARA, Cyclin D1, CDK4, CDK6, and CDKN2A expression in colon cancer cells.
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