Molecular Dynamics Simulation and Essential Dynamics of Deleterious Proline 12 Alanine Single-Nucleotide Polymorphism in PPAR<i>γ</i>2 Associated with Type 2 Diabetes, Cardiovascular Disease, and Nonalcoholic Fatty Liver Disease

<div>GROMACS analysis of Rg, SASA, and intramolecular hydrogen bonds of C<i>α</i> atoms for the mutant and wild type in the PPAR<i>γ</i>2 protein at 300 K. (a) Rg, (b) SASA, and (c) intramolecular hydrogen bonds. Mutant was shown in black and wild type in red.</div>

PPAR Research

fig3

Figure 3

Figure 3: Molecular Dynamics Simulation and Essential Dynamics of Deleterious Proline 12 Alanine Single-Nucleotide Polymorphism in PPAR<i>γ</i>2 Associated with Type 2 Diabetes, Cardiovascular Disease, and Nonalcoholic Fatty Liver Disease 

Figure 3 | Molecular Dynamics Simulation and Essential Dynamics of Deleterious Proline 12 Alanine Single-Nucleotide Polymorphism in PPARγ2 Associated with Type 2 Diabetes, Cardiovascular Disease, and Nonalcoholic Fatty Liver Disease 