Molecular Dynamics Simulation and Essential Dynamics of Deleterious Proline 12 Alanine Single-Nucleotide Polymorphism in PPARγ2 Associated with Type 2 Diabetes, Cardiovascular Disease, and Nonalcoholic Fatty Liver Disease

Figure 6

Superimposition of secondary structures of mutant and wild-type by UCSF Chimera: (a) whole PPARγ2 protein; (b) mutation site, Pro12 allele (red), and 12Ala allele (blue). Mutation site was highlighted in green.

(a)

(b)