α-Bisabolol Mitigates Colon Inflammation by Stimulating Colon PPAR-γ Transcription Factor: In Vivo and In Vitro Study

Figure 2

Effect of bisabolol on Disease Activity Index (DAI), colon length, and myeloperoxidase (MPO) activity. DSS administration increased DAI scores, bisabolol ,and SAZ significantly reduced OR prevented the increase in the DAI scores (a). DSS administration significantly reduced the colon length, and bisabolol and SAZ treatment prevented a decrease in colon length (b, c). DSS administration markedly increased colonic MPO activity. Bisabolol and SAZ significantly prevented the increase in MPO activity (e). Eight to ten animals were used in each group to determine statistical significance. For DAI, the statistics were performed on day eight on the cumulative DAI scores. The data expressed as . , , , and .

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