α-Bisabolol Mitigates Colon Inflammation by Stimulating Colon PPAR-γ Transcription Factor: In Vivo and In Vitro Study

Figure 3

Effect of bisabolol on colon histology. The control colon microarchitecture shows healthy villi and crypts with normal submucosa and muscle layer. DSS administration resulted in focal loss of villi and crypt. The infiltration is reaching submucosa with thickening of muscle layer (a). α-Bisabolol treatment significantly protected the colon microarchitecture with a reduced inflammation score (b). Eight () animals were used in each group to construct colon inflammation scores based on the swiss roll technique. Data are expressed as . and .

(a)

(b)