Peroxisome Proliferator-Activated Receptor <i>γ</i> Regulates Lipid Metabolism in Sheep Trophoblast Cells through mTOR Pathway-Mediated Autophagy

<div>Effects of autophagy activation and inhibition on autophagy-related proteins and lipid metabolism in trophoblast cells. (a) After activating and inhibiting autophagy by rapamycin (RAPA) and 3-MA, respectively, Western blot was used to detect the levels of p-p70S6K, p70S6K, Beclin1, LC3B-II, and LC3B-I proteins at 12 h, 24 h, and 48 h. (b) TG content at different timepoints. (c) MDA content as an indicator of lipid oxidation at different timepoints. Since 3-MA is water-soluble, the control group was also labeled as the nontreatment group (Non) without DMSO. 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PPAR Research

fig2

Figure 2

Figure 2: Peroxisome Proliferator-Activated Receptor <i>γ</i> Regulates Lipid Metabolism in Sheep Trophoblast Cells through mTOR Pathway-Mediated Autophagy 

PPAR Research

Peroxisome Proliferator-Activated Receptor γ Regulates Lipid Metabolism in Sheep Trophoblast Cells through mTOR Pathway-Mediated Autophagy

Figure 2