PPARG and the PTEN-PI3K/AKT Signaling Axis May Cofunction in Promoting Chemosensitivity in Hypopharyngeal Squamous Cell Carcinoma
Table 2
Expression of nine genes compared between the CSP and CNSP groups.
Gene name
All
Normal
Tumor
value
Mean LFC
Std LFC
value
Mean LFC
Std LFC
value
Mean LFC
Std LFC
AKT1
0.02
0.57
0.67
0.50
0.17
0.45
0.26
0.90
1.92
AKT2
0.01
0.66
0.34
0.02
0.67
0.21
0.01
0.97
0.39
AKT3
0.01
2.45
0.97
0.01
3.35
0.97
0.12
0.65
0.45
PIK3CA
0.04
0.76
0.76
0.09
0.80
0.56
0.23
1.56
0.96
PIK3CB
0.16
0.50
0.49
0.16
0.52
0.50
0.17
7.60
0.24
PIK3CD
0.34
0.46
1.41
0.53
0.51
1.90
0.16
0.73
0.71
PIK3CG
0.37
0.57
1.85
0.14
1.41
2.09
0.44
0.47
0.40
PPARG
0.01
1.45
1.66
0.010
2.00
0.31
0.49
0.41
0.80
PTEN
0.01
9.19
0.30
0.040
10.80
0.32
0.76
-0.30
1.59
Note. “Normal” represents the comparison using normal tissue surrounding the tumor. “Tumor” represents comparison using data from tumor tissue. “All” represents using both normal and tumor tissue.
