Table of Contents
Pathology Research International
Volume 2011, Article ID 689521, 10 pages
Research Article

Use of Fine-Needle Aspiration in the Evaluation of Breast Lumps

1Department of Pathology, King Edward Medical University, Lahore 54000, Pakistan
2Department of Pathology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan
3Salford Royal Hospital Trust NHS, University of Manchester, Manchester M13 9PT, UK

Received 10 December 2010; Revised 14 January 2011; Accepted 14 April 2011

Academic Editor: Gary Tse

Copyright © 2011 Mulazim Hussain Bukhari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. A study was designed to see the role of fine needle aspiration cytology (FNAC) in palpable breast lumps. Materials and Methods. Four hundred and twenty five (425) patients came to the Department of Pathology King Edward Medical University, Lahore in four years for FNAC of their palpable breast masses from June 2006 to June 2010. FNAC diagnosis was compared with histological diagnosis to see the accuracy of fine needle aspiration cytology for neoplastic lesions. Results. There were 271/425 benign, 120/425 malignant, and 32/425 suspicious smears. Inadequate samples were repeated twice or thrice, and the degree of success was improved with consecutive repeating approaches. The frequency of inadequacy declined from 86 to 18, and 2 for first, second and third attempts, respectively. The number of repeats increased the diagnostic accuracy of aspirates which is statistically significant ( 𝑃 = . 0 0 0 ). Invasive ductal carcinoma was the most commonly reported lesion with maximum incidence in the 4th, 5th, and 6th decades followed by invasive lobular carcinoma and other malignant lesions. The sensitivity, specificity, accuracy, negative predictive value, and the positive predictive value of FNAC was 98%, 100%, 98%, 100%, and 97%, respectively. Conclusion. FNAC serves as a rapid, economical, and reliable tool for the diagnosis of palpable breast lesions because the cytopathological examination of these lesions before operation or treatment serves as an important diagnostic modality.