Review Article

CpG Island Methylation in Colorectal Cancer: Past, Present and Future

Figure 1

In colorectal cancer, CIMP+ occurs more frequently in tumors of the proximal colon (Figure 1(a)) and less frequently in tumors of the distal colon and rectum (Figure 1(b)). An approximate distribution of genetic and epigenetic tumor alterations is shown.
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(a)
902674.fig.001b
(b)