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Pain Research and Management
Volume 11, Issue 4, Pages 245-247
Case Report

Ondansetron Treatment in a Child Presenting with Chronic Intractable Pruritus

Chantal Frigon and Joëlle Desparmet

Chronic Pain Clinic, Department of Anesthesia, The Montreal Children’s Hospital, Montreal, Quebec, Canada

Copyright © 2006 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The case of a seven-year-old boy with chronic pruritus secondary to a giant congenital melanocytic nevus is presented. The pruritus did not respond to conventional antipruritic drug treatment, but responded to ondansetron, a selective antagonist of 5-hydroxytryptamine type 3 receptors.