How Safe Are Common Analgesics for the Treatment of Acute Pain for Children? A Systematic Review

Figure 2

Risk (incidence rate) of nausea, vomiting, and other minor gastrointestinal symptoms by medication. Other minor gastrointestinal (GI) symptoms included diarrhea, gastric pain, pills being hard to swallow, feeling sick, being unwell with vomiting and reduced urine output, emesis, constipation, sore stomach and abdominal pain, dry mouth, and unspecified GI symptoms. Acet = acetaminophen; ibu = ibuprofen. Results are presented in lowest to highest risk order with placebo at the end (where data were available).