Development of Cardiovascular Indices of Acute Pain Responding in Infants: A Systematic Review

Table 3

Mean and standard deviations for heart rate response to acute pain at less than 7 postnatal days.

Gestational age	Reference	Mean HR (bpm)	SD
25–27 weeks	Craig et al. [24]	172.38	17.22
28–32 weeks	Cong et al. [39]	165.00	14.00
	Craig et al. [24]	168.20	10.50
	Craig et al. [24]	155.25	21.57
	Lucas-Thompson et al. [56]	169.27	10.89
32–34 weeks	Singh et al. [27]	183.40	15.93
	Stevens and Johnston [64]	162.20	15.36
	Stevens et al. [65]	154.00	13.00
	Lucas-Thompson et al. [56]	158.18	15.19
34–37 weeks	Craig et al. [24]	163.20	27.82
	Singh et al. [27]	165.30	16.50
37–42 weeks	Abad et al. [34]	170.00	N/A
	Craig et al. [24]	145.86	19.22
	Campos [38]	174.00	16.60
	Gormally et al. [43]	180.00	N/A
	Gray et al. [45]	123.00	N/A
	Kostandy et al. [51]	155.00	N/A
	Leite et al. [52]	172.70	21.50
	Lindh et al. [55]	134.00	19.00
	Lindh et al. [54]	144.00	20.00
	Oberlander et al. [57]	168.00	N/A
	Shibata et al. [63]	170.00	N/A

Note. denotes numbers that were extrapolated from graphs.