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Pain Research and Management
Volume 2017, Article ID 6264146, 5 pages
Research Article

The Evaluation of the Clinical Effects of Botulinum Toxin on Nocturnal Bruxism

1Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Afyon Kocatepe University, Afyonkarahisar, Turkey
2Vefa Diş Polikliniği, Afyonkarahisar, Turkey
3Uzman DentaClinic, Bursa, Turkey
4Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Bezmialem Vakıf University, İstanbul, Turkey

Correspondence should be addressed to Fatih Asutay; moc.liamtoh@yatusa_td

Received 29 March 2017; Accepted 21 May 2017; Published 5 July 2017

Academic Editor: Lucindo Quintans

Copyright © 2017 Fatih Asutay et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. Nocturnal bruxism can be managed by botulinum toxin (Botox®) in patients who have not responded to conservative treatment. The aim of this study was to evaluate the efficacy of botulinum toxin A (BTXA) in the treatment of nocturnal bruxism. Material and Methods. The retrospective study comprised 25 female patients, aged 23–55 years (mean years). All patients received a single injection of BTXA in the right and left masseters. Evaluation was made by Visual Analogue Scale (VAS) values, complaint duration, onset of effect, and duration of effectiveness. Results. BTXA produced significant improvements in pain scores. Only 2 adverse events (8%) were recorded. Conclusion. BTX-A is effective in the treatment of nocturnal bruxism.