Clinical Study

Clinical Evaluation of a Novel Technology for Oral Patient-Controlled Analgesia, the PCoA® Acute Device, for Hospitalized Patients with Postoperative Pain, in Pilot Feasibility Study

Table 3

Analysis of pill intake time (minutes) by group and by medical center. Analysis was done by nonparametric Wilcoxon-Mann–Whitney method. Analysis of variance (ANOVA) was applied for analyzing the difference in the study outcomes between study centers within study groups (MC: Medical Center).

ParameterAll centersMC-AMC-BMC-C
GroupControl TestControl TestControl TestControl Test

Number of total pills75135215517493731
Number of patients4327209129119
Parameter (minutes)
Mean8.581.178.610.898.381.258.641.55
Std8.040.555.920.4013.660.435.500.68
StdErr0.930.051.290.053.310.060.900.12
Min2.000.382.420.382.000.742.521.03
Median6.331.057.080.864.371.296.751.33
Max60.003.7728.801.6560.002.6228.103.77
value (Wilcoxon test)
value for difference between the centers by group (ANOVA)Control:  
Study: