Research Article

Xm2 Scores for Estimating Total Exposure to Multimodal Strategies Identified by Pharmacists for Managing Pain: Validity Testing and Clinical Relevance

Table 1

Demographic characteristics and pain outcomes of study participants.

CharacteristicTotal (n = 149)Xm2 score (points) value
Low (<16) (n = 73)High (≥16) (n = 76)

Baseline pain (n = 121) mean (standard deviation)6.9 (2.1)6.2 (2.1)7.5 (1.9)<0.01
Age (n = 146) mean (standard deviation)52.5 (13.9)52.5 (13.8)52.4 (14.1)0.94
Sex, female (n = 147) N (%)77 (52.4)36 (50.0)41 (54.7)0.57
Race, white (n = 146) N (%)131 (89.7)64 (90.1)67 (89.3)0.87
Disability (n = 147) N (%)16 (10.9)2 (2.8)14 (18.7)<0.01
Health status (n = 148) N (%)
 Poor/fair26 (17.6)10 (13.9)16 (21.1)0.25
 Good/excellent122 (82.4)62 (86.1)60 (79.0)
Marital status, married (n = 143) N (%)110 (76.9)56 (81.2)54 (73.0)0.25
Employment status, employed (n = 148) N (%)124 (83.8)58 (80.6)66 (86.8)0.30
Primary professional practice site (n = 147) N (%)
 Community58 (39.5)24 (33.3)34 (45.3)0.26
 Hospital25 (17.0)12 (16.7)13 (17.3)
 Other64 (43.5)36 (50.0)28 (37.3)
Completed continuing education on pain management (n = 146) N (%)128 (87.7)59 (81.9)69 (93.2)0.04
Years practiced (n = 146) mean (standard deviation)24.8 (14.5)25.1 (15.0)24.4 (14.1)0.77
Hospital admissions in last five years due to pain (n = 149) N (%)10 (6.7)2 (2.7)8 (10.5)0.10
Emergency department visits in last five years due to pain (n = 148) N (%)20 (13.5)5 (6.9)15 (20.0)0.02
Adverse events from any strategies used (n = 147) N (%)62 (42.2)23 (31.9)39 (52.0)0.01
Pain interference on daily activities (n = 148) N (%)92 (62.2)39 (53.4)53 (70.7)0.03
Pain interference on leisure activities (n = 148) N (%)86 (58.1)35 (48.0)51 (68.0)0.01
Pain interference on relationships (n = 149) N (%)57 (38.3)22 (30.1)35 (46.1)<0.05
Pain interference on work (n = 148) N (%)61 (41.2)23 (31.5)38 (50.7)0.02
Satisfaction with pain management strategies (n = 149) N (%)112 (75.2)61 (83.6)51 (67.1)0.02
Workdays lost in last six months due to pain (n = 138) N (%)28 (20.3)6 (8.6)22 (32.4)<0.01
Pain intensity after treatment (n = 136) mean (standard deviation)3.2 (2.2)3.0 (2.3)3.3 (2.1)0.54
Percent pain relief from all strategies (n = 149) mean (standard deviation)69.1 (20.4)70.8 (20.8)67.4 (20.1)0.32

All comparisons conducted between low- and high-exposure groups using t-test for baseline pain, age, and years practiced and chi-squared test for all remaining variables.