Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China

Table 1

Summary of studies included in the meta-analyses on anxiety and depression in NP.

Study	Sample sizes	Design	Group comparison	Mean age	NP diagnostics	Psychiatric diagnostics
He et al. [19]	58 vs. 1 388	Case-control	NP vs. Np	49.5	Self-rating	SCL-90/STAI
Wang et al. [20]	52 vs. 1 338	Case-control	NP vs. Np	48.25 ± 13.36	Self-rating	SCL-90
Lou et al. [21]	60 vs. 56	Case-control	NP vs. HC	54.31 ± 8.18	Self-rating	SCL-90
Chen et al. [22]	106 vs. 76	Case-control	NP vs. HC	51 ± 8 vs. 48 ± 7	Chinese acknowledged diagnostic criteria	SDS
Fang et al. [23]	89 vs. 60	Case-control	NP vs. HC	49.3 vs. 47.6	Self-rating	SCL-90
Yao et al. [24]	122 vs. 122	Case-control	NP vs. HC	58.86 ± 8.28 vs. 59.36 ± 7.04	Self-rating	SCL-290/SDS/SAS
Zhang et al. [25]	30 vs. 1 338	Case-control	NP vs. Np	52	Chinese acknowledged diagnostic criteria	SCL-90
Wei et al. [26]	217 vs. 1 338	Case-control	NP vs. Np	38.00 ± 5.67	Self-rating	SCL-90
Huang et al. [27]	38 vs. 1 340	Case-control	NP vs. Np	/	Self-rating	SDS/SAS
Wen and Liu [28]	336 vs. 1 340	Case-control	NP vs. Np	/	Self-rating	SDS
Wang et al. [29]	105 vs. 198	Prospective cohort	NP vs. HC	/	Chinese acknowledged diagnostic criteria	Self-rating
Chen et al. [7]	1 026 vs. 1 338	Case-control	NP vs. Np	/	Self-rating	SCL-90
Sun et al. [30]	100 vs. 100	Case-control	NP vs. HC	45.98 ± 8.54 vs. 45.86 ± 8.43	Chinese acknowledged diagnostic criteria	GAD-7/PHQ-9

NP, neck pain; HC, healthy controls; Np, normal population; SCL, symptom check list; STAI, state-trait anxiety inventory; SDS, self-rating depression scale; SAS, self-rating anxiety scale; GAD-7, generalized anxiety disorder-7; and PHQ-9, patient health questionnaire-9.