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Pain Research and Management
Volume 2018, Article ID 4193275, 6 pages
Research Article

Incidence of Delirium in Critically Ill Cancer Patients

1Department of Critical Care Medicine, Instituto Nacional de Cancerología, Mexico City, Mexico
2Department of Critical Care Medicine, Hospital Especialidades Centro Médico Nacional La Raza, Mexican Institute of Social Security, Mexico City, Mexico
3Department of Critical Care Medicine, UMAE Hospital de Traumatologia “Dr. Victor de la Fuente Narvaez”, Mexican Institute of Social Security, Mexico City, Mexico
4Department of Critical Care Medicine, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
5Department of Critical Care Medicine, Medica Sur Clinic & Foundation, Mexico City, Mexico

Correspondence should be addressed to Silvio A. Ñamendys-Silva; xm.ude.nacni@sydnemans

Received 13 December 2017; Revised 13 May 2018; Accepted 25 June 2018; Published 8 July 2018

Academic Editor: Bruno Gagnon

Copyright © 2018 Luis A. Sánchez-Hurtado et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. The aim of this study was to estimate the incidence of delirium and its risk factors among critically ill cancer patients in an intensive care unit (ICU). Materials and Methods. This is a prospective cohort study. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) was measured daily at morning to diagnose delirium by a physician. Delirium was diagnosed when the daily was positive during a patient’s ICU stay. All patients were followed until they were discharged from the ICU. Using logistic regression, we estimated potential risk factors for developing delirium. The primary outcome was the development of ICU delirium. Results. There were 109 patients included in the study. Patients had a mean age of 48.6 ± 18.07 years, and the main reason for admission to the ICU was septic shock (40.4%). The incidence of delirium was 22.9%. The mortality among all subjects was 15.6%; the mortality rate in patients who developed delirium was 12%. The only variable that had an association with the development of delirium in the ICU was the days of use of mechanical ventilation (OR: 1.06; CI 95%: 0.99–1.13;). Conclusion. Delirium is a frequent condition in critically ill cancer patients admitted to the ICU. The duration in days of mechanical ventilation is potential risk factors for developing delirium during an ICU stay. Delirium was not associated with a higher rate of mortality in this group of patients.