Serum Analysis in Patients with Temporomandibular Disorders: A Controlled Cross-Sectional Study in Norway

Table 2

Gender-matched serum analyses: Results from serum analyses showed mean levels statistically differed between TMD patients and controls, divided into subgroups of women and men. The second column shows normal values for women and men at all ages. Significantly higher levels of hemoglobin (), cobalamin (), albumin (), PTH (), and vitamin D () were observed in women in the TMD group. Significantly lower levels of creatinine () and potassium (0.002) were observed in women in the TMD group. Significantly higher levels of TSH () and albumin () were observed in men in the TMD group. The number of men was considerably smaller in both groups.

Gender-matched serum analyses	Reference values	TMD (n = 60)			Control (n = 60)			-value (paired t-test)
		Mean	±SD	Range	Mean	±SD	Range	( = sign.)
Hemoglobin
Women (n = 51 + 51)	11.7–15.3 g/dL	13.9	1.22	8.1, 15.7	13.6	0.70	11.5, 14.7	0.045
Men (n = 9 + 9)	13.4–17.0 g/dL	15.2	1.13	13.4, 16.2	14.9	0.62	14.0, 16.0	0.288
TSH
Women (n = 51 + 51)	0.4–4.5 mlE/L	1.52	0.82	0.01, 4.31	1.80	1.04	0.14, 4.72	0.111
Men (n = 9 + 9)	0.4–4.5 mlE/L	2.24	0.59	1.25, 3.34	1.84	0.52	1.17, 2.49	0.040
Cobalamin
Women (n = 51 + 51)	175–700 pmol/L	425	210.0	167, 1322	355	128.4	129, 702	0.020
Men (n = 9 + 9)	175–700 pmol/L	401	60.67	310, 455	403	100.3	291, 568	0.483
Creatinine
Women (n = 51 + 51)	45–90 umol/L	62.8	8.01	45, 81	66.2	8.77	49, 84	0.018
Men (n = 9 + 9)	60–105 umol/L	81.3	8.93	68, 93	88.9	9.97	74, 108	0.098
Potassium
Women (n = 51 + 51)	3.5–5.0 mmol/L	4.0	0.25	3.2, 4.6	4.1	0.30	3.4, 5.3	0.002
Men (n = 9 + 9)	3.5–5.0 mmol/L	4.1	0.21	3.9, 4.5	4.0	0.33	3.5, 4.5	0.267
Albumin
Women (n = 51 + 51)	Age dependent <39y: 39–50, 40–69y: 39–48,	45.9	2.98	40.0, 53.0	44.9	1.91	40.0, 49.0	0.017
Men (n = 9 + 9)	>70y: 36–48 g/L	48.0	2.08	45.0, 51.0	46.6	1.59	44.0, 48.0	0.026
PTH
Women (n = 51 + 51)	1.3–6.8 pmol/L	3.5	1.58	0.9, 8.2	2.9	1.03	1.0, 5.2	0.040
Men (n = 9 + 9)	1.3–6.8 pmol/L	2.7	1.10	1.1, 4.2	2.58	1.39	1.4, 6.0	0.385
Vitamin D
Women (n = 51 + 51)	50–113 nmol/L	75.3	26.23	19.0, 187.0	61.8	19.78	22.0, 127.0	0.002
Men (n = 9 + 9)	50–113 nmol/L	55.8	26.21	21.0, 111.0	57.6	11.02	42.0, 72.0	0.426