Research Article

Curcumin Protects Human Umbilical Vein Endothelial Cells against H2O2-Induced Cell Injury

Figure 4

The effect of curcumin on cell death-related genes in H2O2-exposed HUVECs. HUVECs were pretreated with curcumin (40 μM and 50 μM) for 12 h and with H2O2 (100 μM) treatment for another 12 h. The mRNA level of cell death-related genes including p53, p21, Bax, and Bcl-2 was detected by PCR. The expression of apoptosis protein caspase3 was evaluated by western blot. and , n = 3.
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