Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats

<div>Three immunolabeling of Iba1/DAPI with BDNF (a), PI3K (b), and p-ERK (c). At a higher magnification, almost all BDNF, PI3K, and p-ERK immunofluorescence colocalized with the nuclear marker DAPI. The localization of BDNF, PI3K, and p-ERK in microglia was confirmed by triple labeling with BDNF/Iba1/DAPI, PI3K/Iba1/DAPI, and p-ERK/Iba1/DAPI. Scale bar: 100 <i>μ</i>m.</div>

Pain Research and Management

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Figure 2

Figure 2: Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats 

Figure 2 | Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats 