Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats

Figure 4

Real-time PCR analysis of Iba1, BDNF, PI3K, and p-ERK mRNA expression in the spinal cord in different groups on D14. Values represent the relative ratio of Iba1, BDNF, PI3K, and p-ERK mRNA (normalized to GAPDH mRNA) expression to that in the Sham rats. Each symbol represents mean ± SEM. In the Iba1 assay, against the Sham group and against the SNI group. In the BDNF assay, against the Sham group and against the SNI group. In the PI3K assay, against the Sham group and against the SNI group. In the p-ERK assay, against the Sham group and against the SNI group. LSD t test, n = 5 rats per assay.