Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats

Figure 5

Expression of Iba1 (a), BDNF (b), PI3K (c), and p-ERK (d) in the spinal cord of rats in different groups (immunofluorescence, ×100), scale bar = 100 μm. (e) The intensity of Iba1, BDNF, PI3K, and p-ERK immunofluorescence in the spinal cord in different groups on D14. Each symbol represents mean ± SEM. In the BDNF assay, against the Sham group and against the SNI group. In the PI3K assay, against the Sham group and against the SNI group. In the p-ERK assay, against the Sham group and against the SNI group. In the Iba1 assay, against the Sham group and against the SNI group. LSD t test, n = 5 rats per assay.

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