Electroacupuncture Treatment Suppresses Transcription Factor IRF8 in Spinal Cord of Rats with Spared Nerve Injury

Figure 6

Immunofluorescence staining evaluated the effect of 2 Hz EA on coexpression of spinal CX3CRl with CD11b following SNI. CX3CRl and CD11b were double-stained in the spinal dorsal horn from the sham, SNI, and SNI + EA group rats (scale bar = 20 μm). Immunofluorescence staining data revealed that the SNI improved spinal CX3CRl and CD11b expression compared to the sham group. 2 Hz EA treatment reversed the coexpression of CX3CRl (green) with microglial activation indicator CD11b (red) in the spinal cord of SNI rats.