Effectiveness of Acupuncture Treatment on Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized, Assessor-Blinded, Controlled Trial
Table 4
Comparison of changes of NCS within and between groups.
Variables
Time
Acupuncture group (N = 19)
Vit B1 and gabapentin group (N = 19)
Comparison between two groups
Mean (SD)
Mean diff.a(95% CI)
P value
Mean (SD)
Mean diff.a (95% CI)
P value
Mean diff. (95% CI)
P value
Sural nerve
Onset latency, ms
Baseline
2.58 (1.40)
2.51 (1.38)
4 weeks
2.37 (1.09)
−0.21 (−0.62 to 0.20)
0.30
2.51 (1.40)
0.004 (−0.51 to 0.52)
0.988
−0.21 (−0.85 to 0.42)
0.50
Amplitude, μv
Baseline
3.56 (2.48)
3.62 (2.20)
4 weeks
6.62 (3.60)
3.06 (1.78 to 4.34)
<0.001
3.98 (2.49)
0.35 (−0.68 to 1.39)
0.482
2.7 (1.11 to 4.30)
0.002
SCV, m/s
Baseline
34.05 (18.46)
33.79 (18.29)
4 weeks
39.21 (17.72)
5.16 (0.41 to 9.90)
0.04
34.42 (18.61)
0.63 (−6.82 to 8.08)
0.861
4.53 (−4.00 to 13.05)
0.29
Peroneal nerve
Onset latency
Baseline
3.57 (1.36)
3.50 (1.42)
4 weeks
3.37 (1.26)
−0.20 (−0.37 to −0.04)
0.02
3.51 (1.38)
0.02 (−0.20 to 0.24)
0.865
−0.22 (−0.49 to 0.05)
0.11
Amplitude
Baseline
3.00 (1.52)
3.23 (2.25)
4 weeks
3.82 (2.40)
0.82 (0.11 to 1.52)
0.03
3.24 (2.14)
0.005 (−0.44 to 0.45)
0.979
0.81 (0.006 to 1.62)
0.052
MCV
Baseline
36.57 (13.61)
37.02 (13.59)
4 weeks
39.45 (14.45)
2.87 (1.16 to 4.58)
0.002
37.26 (13.63)
0.24 (−1.44 to 1.93)
0.766
2.63 (0.32 to 4.95)
0.03
Tibial nerve
Onset latency
Baseline
4.64 (1.31)
4.53 (1.89)
4 weeks
4.35 (1.25)
−0.29 (−0.57 to −0.01)
0.04
4.52 (1.82)
−0.01 (−0.34 to 0.32)
0.937
−0.28 (−0.69 to 0.14)
0.19
Amplitude
Baseline
5.63 (2.52)
5.75 (3.28)
4 weeks
6.80 (2.92)
1.17 (0.65 to 1.68)
<0.001
5.77 (2.92)
0.03 (−0.37 to 0.43)
0.891
1.14 (0.51 to 1.77)
0.001
MCV
Baseline
38.74 (10.07)
38.22 (13.99)
4 weeks
40.81 (10.54)
2.08 (0.89 to 3.26)
0.002
38.29 (13.90)
0.07 (−0.85 to 0.99)
0.878
2.01 (0.56 to 3.46)
0.008
values from within-group comparison using the paired samples test. values from between-group comparison using the independent samples test. aMean difference from baseline. NCS = nerve conduction study. SCV = sensory conduction velocity. MCV = motor conduction velocity.
