Efficacy and Safety of Ultrasound-Guided Radiofrequency Treatment for Chronic Pain in Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Does the design or analysis control account for important confounding and modifying variables through matching, stratification, multivariable analysis, or other approaches?
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Performance bias
Did researchers rule out any impact from a concurrent intervention or an unintended exposure that might bias results?
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Did the study maintain fidelity to the intervention protocol?
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Attrition bias
If attrition (overall or differential nonresponse, dropout, loss to follow-up, or exclusion of participants) was a concern, were missing data handled appropriately (e.g., intention-to-treat analysis and imputation)?
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Detection bias
Were the outcome assessors blinded to the intervention or exposure status of participants?
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Were interventions/exposures assessed/defined using valid and reliable measures implemented consistently across all study participants?
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Were outcomes assessed/defined using valid and reliable measures implemented consistently across all study participants?
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Were confounding variables assessed using valid and reliable measures implemented consistently across all study participants?
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Reporting bias
Were the potential outcomes prespecified by the researchers? Were all prespecified outcomes reported?