Impact of the Timing of Rocuronium Injection after Propofol Administration on Temporal Summation of Pain in Gynecologic Laparoscopic Surgery: A Prospective and Controlled Study
Table 2
Perioperative data.
PRi group (n = 48)
PRd group (n = 47)
value
Basal BIS
95.1 ± 2.7
95.1 ± 2.8
0.99
BIS immediately after propofol injection
94.9 ± 2.2
95.0 ± 1.7
0.96
Average BIS less than 60
57.7 ± 1.7
57.7 ± 2.2
0.96
Time to get BIS less than 60 (sec)
28.4 ± 5.0
35.1 ± 4.9
0.00
The incidence of propofol injection pain
25 (52.1)
26 (55.3)
0.75
VAS for propofol injection pain
35.6 ± 12.6
36.9 ± 14.1
0.70
The grade of rocuronium-induced withdrawal movement
—
—
0.019
1 (no withdrawal)
15 (31.3)
26 (55.3)
—
2 (wrist withdrawal)
0 (0)
0 (0)
—
3 (arm only)
22 (45.8)
18 (38.3)
—
4 (generalized movement)
11 (22.9)
3 (6.4)
—
VAS for pain at 1 hr after surgery
43.5 ± 11.9
42.1 ± 9.8
0.53
VAS for pain at 24 hr after surgery
35.4 ± 12.0
32.6 ± 8.5
0.18
VAS for pain at 48 h after surgery
24.4 ± 10.1
21.7 ± 7.0
0.14
PCA opioid consumption at 24 h after surgery
52.7 ± 4.0
51.6 ± 3.8
0.14
PCA opioid consumption at 48 h after surgery
50.5 ± 2.8
49.8 ± 2.2
0.20
Total PCA opioid consumption for 48 h after surgery
103.1 ± 6.3
100.3 ± 9.5
0.10
Rescue analgesics
0.30
Ketorolac
19 (39.6)
25 (53.2)
—
Fentanyl
26 (54.2)
18 (38.3)
—
Complications on vein
Tenderness
3 (6.3)
1 (2.1)
0.32
Redness
4 (6.3)
2 (4.3)
0.41
Hardness
1 (2.1)
0 (0)
0.32
Tenderness and hardness
1 (2.1)
0 (0)
0.32
Recall
Pain/respiratory difficulty
5 (10.4)/0 (0)
4 (8.5)/0 (0)
0.75
Values are expressed as mean ± SD or numbers (%). PCA, patient-controlled analgesia; VAS, visual analog scale.
