Clinical Study

Predicting Acute Postoperative Pain Trajectories and Long-Term Outcomes of Adolescents after Spinal Fusion Surgery

Table 1

Preoperative and intraoperative variables of study patients (n = 106).

Preoperative and intraoperative variablesTotal patient sample (n = 106)Pain trajectory
1 (n = 26)2 (n = 29)3 (n = 26)4 (n = 25)

Demographics
Age, years15.4 (2.0)15.7 (2.0)15.5 (2.1)14.9 (1.6)15.4 (2.2)
Sex, n (%)
 Male25 (23.6)8 (30.8)7 (24.1)8 (30.8)2 (8.0)
 Female81 (76.4)18 (69.2)22 (75.9)18 (69.2)23 (92.0)

Largest cobb angle, °56.8 (12.6)54.2 (14.3)55.0 (13.1)60.7 (11.5)57.6 (10.6)
Pain catastrophizing status
Total PCS-c score22.9 (9.8)
Pain catastrophizers, n (%)
 No80 (75.5)24 (92.3)20 (69.0)21 (80.8)15 (60.0)
 Yes26 (24.5)2 (7.7)9 (31.0)5 (19.2)10 (40.0)

SRS-30 variables, n (%)
Pain in last 6 months
 None9 (8.5)4 (15.4)0 (0)2 (7.7)3 (12.0)
 Mild34 (32.1)16 (61.5)8 (27.6)4 (15.4)6 (24.0)
 Moderate to severe62 (58.5)6 (23.1)21 (72.4)19 (73.1)16 (64.0)
Pain in last 1 month
 None13 (12.3)7 (26.9)2 (6.9)2 (7.7)2 (8.0)
 Mild29 (27.4)10 (38.5)6 (20.7)6 (23.1)7 (28.0)
 Moderate to severe64 (60.4)9 (34.6)21 (72.4)18 (69.2)16 (64.0)
Back pain at rest
 No17 (16.0)5 (19.2)4 (13.8)6 (23.1)2 (8.0)
 Yes89 (84.0)21 (80.8)25 (86.2)20 (77)23 (92.0)
Current level of activity
 Full activities without restriction45 (42.5)13 (50)13 (44.8)11 (42.3)8 (32.0)
 Light-to-moderate activity45 (42.5)9 (34.6)11 (37.9)9 (34.6)16 (64.0)
 No activity16 (15.1)4 (15.4)5 (17.2)6 (23.1)1 (4.0)
Missed school/work days due to back pain in last 3 months
 075 (70.8)21 (80.8)22 (75.9)16 (61.5)16 (64.0)
 1–317 (16.0)3 (11.5)4 (13.8)4 (15.4)6 (25.0)
 4 or more13 (12.3)2 (7.7)3 (10.3)6 (23.1)2 (8.0)
Medications for pain, n (%)
 None78 (73.6)24 (92.3)23 (79.3)15 (57.7)16 (64.0)
 Yes
  Nonopioids22 (20.8)2 (7.7)4 (13.8)9 (34.6)7 (28.0)
  Opioids6 (5.7)0 (0)2 (6.9)2 (7.7)2 (8.0)

Anesthetic variables
Remifentanil, mg/kg45.6 (22.9)37.0 (23.3)45.5 (21.2)51.7 (23.2)48.5 (22.4)
Sufentanil, mg/kg (n = 28)0.56 (0.52)0.26 (0.14)0.67 (0.65)0.45 (0.37)0.79 (0.65)
Fentanyl, mg/kg (n = 14)2.30 (0.55)2.7 (1.3)2.2 (0.45)2.5 (0.35)2.0 (0.38)
Dexamethasone, mg/kg0.11 (0.04)0.12 (0.03)0.10 (0.01)0.12 (0.04)0.12 (0.04)
Ketamine, mg/kg0.70 (0.57)0.70 (0.45)0.73 (0.52)0.74 (0.50)0.72 (0.81)
Spinal morphine, mg/kg5.40 (2.97)5.28 (2.77)5.96 (3.92)5.11 (1.62)5.19 (3.05)
Total intraoperative opioids (equivalents of morphine), mg/kg36.1 (17.0)29.5 (17.7)36.3 (15.8)40.7 (17.1)38.3 (16.6)

Surgical variables
Surgery length, minutes264.6 (76.4)254.7 (71.6)260.3 (75.8)277.3 (76.5)266.5 (84.1)
Blood loss, mL761.1 (441.2)769.5 (437.4)790.5 (509.1)721.7 (300.0)759.5 (503.3)
Number of fused vertebrae10.6 (2.6)10.2 (2.8)10.0 (2.9)11.5 (1.6)10.9 (2.5)

Data are presented as mean (SD), unless otherwise specified. PCSc: Pain Catastrophizing Scalechild questionnaire, SRS-30: Scoliosis Research Society questionnaire: version 30. Significant association observed between the variable and pain trajectory membership.