Injection of Lidocaine Alone versus Lidocaine plus Dexmedetomidine in Impacted Third Molar Extraction Surgery, a Double-Blind Randomized Control Trial for Postoperative Pain Evaluation

Table 2

The mean pain scores and number of painkillers used in the two groups at different times.

Variable	Time	Intervention	Control	value	Spearman (r)	Spearman value
Pain scores (mean ± SD)	0	0.25 ± 0.44	0.8 ± 1.00	0.031	−0.33	0.03
	6	4.40 ± 2.50	7.55 ± 2.03	<0.001	−0.37	0.01
	12	2.80 ± 2.52	5.50 ± 2.39	0.003	−0.46	<0.01
	24	1.60 ± 2.37	4.00 ± 2.49	0.003	−0.17	0.26
Painkillers used (number ± SD)	6	1.4 ± 0.75	1.6 ± 0.75	0.313	—	—
	12	0.75 ± 0.55	1.1 ± 0.71	0.109	—	—
	24	0.45 ± 0.60	0.70 ± 0.80	0.348	—	—

Time, time after the surgery (hours); intervention, intervention group (dexmedetomidine + lidocaine); control, control group (lidocaine); Spearman (r): Spearman correlation (r).