|
| First author, year | Article title | Pain model | Study design, n patients | Inclusion criteria | Intervention (HBOT pressure, duration, n of sessions) | Comparator/control |
|
| Kiralp, 2004 [33] | Effectiveness of hyperbaric oxygen therapy in the treatment of complex regional pain syndrome | CRPS | RCT, n = 71 (37 intervention, 34 placebo) | Clinical CRPS, type I or II | 2.4 ATA, 90 min x 15 | Placebo: 2.4 ATA breathing air, 90 min x 15, once daily |
|
| Peach, 1995 [35] | Hyperbaric oxygen and the reflex sympathetic dystrophy syndrome: a case report | CRPS | Observational case reports, n = 1 | Clinical CRPS, type I | 2.8 ATA, 46 min x1 + 2.0 ATA, 90 min x 1 + 2.4 ATA, 90 min x 1 | None |
|
| Williams, 2009 [36] | Chronic regional pain syndrome after subtalar arthrodesis is not prevented by early hyperbaric oxygen | CRPS | Observational case reports, n = 1 | Clinical CRPS type I, Norman Harden and Bruehl diagnostic criteria | 2.2 ATA, 90 min x 19 | None |
|
| Katznelson, 2016 [37] | Successful treatment of lower limb complex regional pain syndrome following three weeks of hyperbaric oxygen therapy | CRPS | Observational case reports, n = 1 | Clinical CRPS, type I | 2.4 ATA, 90 min x 15 | None |
|
| Binkley, 2019 [38] | Successful treatment of long standing complex regional pain syndrome with hyperbaric oxygen therapy | CRPS | Observational case reports, n = 1 | Clinical CRPS, type I | 2.4 ATA, 90 min x 40. Second course 7 months later, 2.0 ATA, 90 min x 33. | None |
|
| van Ophoven, 2004 [39] | Hyperbaric oxygen for the treatment of interstitial cystitis: long-term results of a prospective pilot study | IC | Observational prospective case series, n = 6 | Symptom criteria of the National Institute of Diabetes, Digestive and Kidney Diseases for IC | 2.4 ATA, 90 min x 30 | None |
|
| van Ophoven, 2006 [40] | Safety and efficacy of hyperbaric oxygen therapy for the treatment of interstitial cystitis: A randomized, sham controlled, double-blind trial | IC | RCT, double-blind, sham controlled, n = 21 (14 intervention, 7 placebo) | Diagnostic criteria of the National Institute of Diabetes and Digestive and Kidney Diseases for IC | 2.4, 90 min x 30 | Placebo: 1.3 ATA breathing air, 90 min x 30, once daily |
|
| Tanaka, 2011 [41] | Hyperbaric oxygen therapy for painful bladder syndrome/interstitial cystitis resistant to conventional treatments: long-term results of a case series in Japan | IC | Observational prospective case series, n = 11 | Diagnostic criteria of the National Institute of Diabetes and Digestive and Kidney Diseases for IC | 2.0 ATA, 60 min x 10 (8 pts) or x 20 (3 pts) | None |
|
| Wenzler, 2017 [42] | Treatment of ulcerative compared to nonulcerative interstitial cystitis with hyperbaric oxygen: a pilot study | IC | Observational prospective pilot case series, n = 9 | Diagnostic criteria of the National Institute of Diabetes and Digestive and Kidney Diseases for IC | 2.2 ATA, 90 min x 30 | None |
|
| Pritchard, 2011 [43] | Double-blind randomized phase II study of hyperbaric oxygen in patients with radiation-induced brachial plexopathy | RIBP | RCT, double-blind, sham controlled, n = 34 (17 intervention, 17 placebo) | Confirmation of RIBP, freedom from cancer recurrence, fitness for HBOT | 2.4 ATA, 90 min x 30 | Placebo: 2.4 ATA breathing 41% oxygen, 90 min x 30 |
|
| Videtic, 1999 [44] | Hyperbaric oxygen corrects sacral plexopathy due to osteoradionecrosis appearing 15 years after pelvic irradiation | Sacral plexopathy | Observational case reports, n = 1 | Clinical diagnosis | 2.5 ATA, 90 min x 30 | None |
|
| Stowe, 2020 [45] | Hyperbaric oxygen therapy for radiation-induced brachial plexopathy, a case report and literature review | RIBP | Observational case reports, n = 1 | Clinical and radiographic diagnosis | 2.4 ATA, 120 min x 30 | None |
|
| Peng, 2012 [46] | Effect of hyperbaric oxygen therapy on patients with herpes zoster | PHN | RCT, not blinded, n = 68 (36 intervention, 32 control) | Clinical diagnosis of acute herpes zoster | 2.2 ATA, 80 min x 30, twice a day + medical therapy [antiviral (acyclovir), nerve nutritive (mecobalamin), pain relief (tramadol), and antidepressive (nortriptyline)] | Controls: only medical therapy |
|
| Gu, 2012 [18] | Hyperbaric oxygen therapy attenuates neuropathic hyperalgesia in rats and idiopathic trigeminal neuralgia in patients | TN | RCT, n = 42 (22 intervention, 20 placebo) | Clinical diagnosis of idiopathic TN | 1.8 ATA, 70 min x 10 | Placebo: 1.03 ATA breathing air, 70 min x 10 |
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