Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations

Table 1

Characteristics and summary of recommendations of medical cannabis for chronic pain management.

First author/organization	Publication year	Geographic region	Type of publication	Condition	Direction and strength of recommendation	Additional recommendations
Acevedo [18]	2009	Latin America	Guideline	Neuropathic pain associated with multiple sclerosis	Weak in favor	Not provided
Allan/CFP [26]	2018	Canada	Guideline	Neuropathic pain	Weak in favor	Recommend against as first- or second-line therapy
Australian DoH [21]	2017	Australia	Guideline	Chronic noncancer pain	Weak in favor	Recommend against as first-line therapy
Bruce/HIVMA of IDSA [24]	2017	United States	Guideline	Chronic pain in people living with HIV	Weak in favor	Not provided
Andrews/CAG [23]	2019	Canada	Evidence-based statement	Chronic abdominal pain listed in nonspecified gastrointestinal symptoms	Weak in favor	Recommend against as first-line therapy
CRA [27]	2019	Canada	Evidence-based statement	Rheumatic pain	Weak in favor	Recommend against as an alternative to standard care
Dworkin/IASP [19]	2007	United States	Evidence-based recommendation	Neuropathic pain associated with multiple sclerosis	Weak in favor	Recommend against as first- or second-line therapy
Häuser/EFIC [28]	2018	Europe	Evidence-based statement	Chronic noncancer pain	Weak in favor	Recommend against as first- or second-line therapy
Moulin/CPS [29]	2014	Canada	Evidence-based statement	Neuropathic pain	Weak in favor	Recommend against as first- or second-line therapy
NICE [20]	2013	United Kingdom	Evidence-based recommendation	Neuropathic pain	Weak in favor	Recommend against in nonspecialist settings
Sahraian [22]	2018	Iran	Evidence-based recommendation	Neuropathic pain associated with multiple sclerosis	Weak in favor	Not provided
Yadav/AAN [25]	2014	United States	Guideline	Neuropathic pain associated with multiple sclerosis	Weak in favor	Recommend against for central neuropathic pain

AAN = American Academy of Neurology; Australian DoH = The Australian Government Department of Health; CAG = Canadian Association of Gastroenterology; CFP = Canadian Family Physician; CPS = Canadian Pain Society; CRA = Canadian Rheumatology Association; EFIC = European Pain Federation, formerly the European Federation of IASP Chapters; HIV = Human Immunodeficiency Virus; HIVMA of IDSA = HIV Medicine Association of Infectious Diseases Society of America; IASP = the International Association for the Study of Pain; NICE = the National Institute for Health and Care Excellence.