Decreased Gray Matter Volume in the Frontal Cortex of Migraine Patients with Associated Functional Connectivity Alterations: A VBM and rs-FC Study

Figure 1

VBM results showed decreased gray matter volume in the left middle frontal cortex (lower) in MwoA patients compared with HCs. rs-FC analysis showed the middle frontal cortex (lower) had a decreased functional connectivity between the middle frontal cortex (upper) and the posterior cingulate cortex in MwoA-DI patients compared with HCs. The middle frontal cortex (lower) had a decreased functional connectivity between the middle frontal cortex (upper) in MwoA-DI patients compare with MwoA-DA patients. The middle frontal cortex (lower) had an increased functional connectivity with left cerebellar lobule VI in MwoA-DA patients compared with HCs.