Analgesic Efficacy of Intravenous Ibuprofen in the Treatment of Postoperative Acute Pain: A Phase III Multicenter Randomized Placebo-ControlledDouble-Blind Clinical Trial

Figure 5

Distribution of surgery patients randomized to receive IVIB or placebo for postoperative pain. PCA, patient-controlled analgesia. FAS, full analysis set including all patients who were randomized and received at least a partial dose of IV ibuprofen or placebo; VAD, valid data set including all patients who receive at least 4 doses of IV ibuprofen or placebo as required by the study protocol; SS, safety set, including all patients who received at least a dose of IV ibuprofen or placebo and safety assessment after randomization. Reasons for exclusion from the efficacy population included adverse events, noncompliance, lack of efficacy, and withdrawn consent.