Analgesic Efficacy of Intravenous Ibuprofen in the Treatment of Postoperative Acute Pain: A Phase III Multicenter Randomized Placebo-ControlledDouble-Blind Clinical Trial
Table 1
Demographic profiles and other information about patients.
Characteristics
Placebo group (n = 119)
IVIB 400 mg group (n = 115)
IVIB 800 mg group (n = 111)
Age (y); M ± StD
52.89 ± 10.66
52.79 ± 12.45
52.95 ± 11.13
Gender; n (%)
Male
62 (52.10)
63 (54.78)
67 (60.36)
Female
57 (47.90)
52 (45.22)
44 (39.64)
Ethnicity; n (%)
Han
117 (98.32)
114 (99.13)
109 (98.20)
Other
2 (1.68)
1 (0.87)
2 (1.80)
Height (cm); M ± StD
164.26 ± 7.65
164.26 ± 7.93
164.77 ± 8.26
Weight (Kg); M ± StD
62.54 ± 11.18
61.90 ± 11.60
61.50 ± 10.35
BMI (Kg/m2); M ± StD
23.10 ± 3.29
22.82 ± 3.18
22.56 ± 2.77
Smoking history; n (%)
No
97 (81.51)
88 (76.52)
84 (75.68)
Yes
22 (18.49)
27 (23.48)
27 (24.32)
History of alcohol consumption; n (%)
Never
96 (80.67)
85 (73.91)
93 (83.78)
Occasionally
11 (9.24)
17 (14.78)
5 (4.50)
Frequently
12 (10.08)
13 (11.30)
13 (11.71)
History of drug dependence; n (%)
No
117 (98.32)
115 (100.00)
111 (100.00)
Yes
2 (1.68)
0 (0.00)
0 (0.00)
History of drug allergy; n (%)
No
110 (92.44)
106 (92.17)
109 (98.20)
Yes
9 (7.56)
9 (7.83)
2 (1.80)
Previous surgical history; n (%)
No
105 (88.24)
100 (86.96)
94 (84.68)
Yes
14 (11.76)
15 (13.04)
17 (15.32)
Another previous medical history within the past 1 y; n (%)
No
59 (49.58)
60 (52.17)
61 (54.95)
Yes
60 (50.42)
55 (47.83)
50 (45.05)
Type of surgery; n (%)
Abdominal surgery
58 (48.74)
60 (52.17)
56 (50.45)
Orthopaedic surgery
61 (51.26)
55 (47.83)
55 (49.55)
Classification of ASA; n (%)
I
31 (26.05)
25 (21.74)
27 (24.32)
II
86 (72.27)
88 (76.52)
84 (75.68)
III
2 (1.68)
2 (1.74)
0 (0.00)
Duration of surgery (min); M ± StD
206.19 ± 95.93
215.61 ± 88.97
205.50 ± 98.09
Whether to use prophylactic antiemetic drugs; n (%)
No
25 (21.01)
27 (23.48)
28 (25.23)
Yes
94 (78.99)
88 (76.52)
83 (74.77)
y: years, cm: centimeter, Kg: kilogram, min: minutes, ASA: American Society of Anesthesiologists. M ± StD: means ± standard deviation.
