Pain Research and Management / 2023 / Article / Tab 2 / Research Article
Analgesic Efficacy of Intravenous Ibuprofen in the Treatment of Postoperative Acute Pain: A Phase III Multicenter Randomized Placebo-ControlledDouble-Blind Clinical Trial Table 2 AEs related to IVIB and morphine. (%) of patients.
Events; n (%) Placebo (n = 119) IVIB 400 mg (n = 115) IVIB 800 mg (n = 111) Gastrointestinal dysfunction Naupathia 12 (10.08) 8 (6.96) 11 (9.91) 0.6487 Vomiting 10 (8.40) 4 (3.48) 8 (7.21) 0.2693 Flatulence 0 (0.00) 0 (0.00) 1 (0.90) 0.3217 Constipation 0 (0.00) 1 (0.87) 2 (1.80) 0.2129 Nervous system Headache 0 (0.00) 0 (0.00) 2 (1.80) 0.1029 Dizziness 1 (0.84) 1 (0.87) 3 (2.70) 0.4551 Sedation 0 (0.00) 0 (0.00) 1 (0.90) 0.3217 Renal dysfunction Elevated serum creatinine 0 (0.00) 1 (0.87) 0 (0.00) 0.6551 Gastrointestinal bleeding 0 (0.00) 1 (0.87) 0 (0.00) 0.6551 Cardiovascular events Hypotension 3 (2.52) 2 (1.74) 2 (1.80) 1 Fluctuation of blood pressure 0 (0.00) 1 (0.87) 0 (0.00) 0.6551 Allergic reactions/rash Skin rash 0 (0.00) 1 (0.87) 0 (0.00) 0.6551 Allergic dermatitis 2 (1.68) 0 (0.00) 0 (0.00) 0.3317 Hypersensitivity 1 (0.84) 0 (0.00) 0 (0.00) 1 Gastrointestinal bleeding 0 (0.00) 1 (0.87) 0 (0.00) 0.6551 Pruritus 0 (0.00) 1 (0.87) 0 (0.00) 0.6551 Urinary retention 2 (1.68) 1 (0.87) 2 (1.80) 0.8709 Respiratory depression 0 (0.00) 0 (0.00) 0 (0.00) Thrombophlebitis 0 (0.00) 0 (0.00) 0 (0.00)
AEs: adverse events.
