Currently, temporomandibular disorders (TMD) refer to the causes responsible for the impaired function of the temporomandibular joints and the associated neuro-muscular system, which may provoke pain and dysfunction of the masticatory system. The term TMD is not a diagnosis but rather a broad term that contains a number of disease entities, such as pain in masticatory muscles and temporomandibular joints, headache, disturbances in jaw movements with or without sounds while opening and closing the mouth.

TMD is the second most common musculoskeletal pain condition after chronic low back pain. Temporomandibular disorders have become a widespread social and economic problem for which annual spending only in North America is estimated at billions of US dollars. In recent years, there has been a very large and varied development of research focused on the etiology, epidemiology, systematization, and management of TMD. Therefore, it is important to understand that only an accurate and broad sensed explanation of etiopathogenesis and the unification of taxonomy provide an exhaustive understanding of TMD.

The Special Issue aims at collecting multidisciplinary approaches to the pain of temporomandibular disorders in basic and clinical aspects. The current views included in this issue will hopefully allow us to assess the perspective on TMD, and to develop and familiarize with new researches related to multidisciplinary viewpoints.

Potential topics include but are not limited to the following:

• Basic research on TMD pain etiology
• Clinical research on TMD pain management
• TMD pain epidemiology with or without financial aspects
• TMD pain diagnostics (especially with clinical assessment of diagnostic tool validity)
• Current approaches to multidisciplinary management of TMD pain
• Conservative methods for TMD pain management
• Invasive methods for TMD pain management
• Drug therapy in TMD pain management
• Dental management of TMD pain
• Comorbidities in TMD pain
• Diseases entities that can affect TMD pain
• Relationship between temporomandibular disorders and sleep
• Imaging in temporomandibular disorders
• Dependence between temporomandibular disorders and awake bruxism and sleep bruxism