Development of Viral Vectors for Gene Therapy for Chronic Pain

Table 3

Analgesic effect of AV vectors encoding therapeutic genes in chronic pain treatment.

Pain models	Gene product	Inoculation	References
Inflammatory pain; Pathological pain; Inflammatory pain; Neuropathic pain	GAD65; IL-10; β-endorphin; Interleukin-2	Injected into the left trigeminal ganglion; Intrathecal administration; Intrathecal administration; Intrathecal administration	Vit et al. [43]; Milligan et al. [31]; Finegold et al. [44]; Yao et al. [46]