Review Article
A Review on the Fascinating World of Insect Resources: Reason for Thoughts
Table 4
Components of bee venom and their major characteristics.
| | Components | MW | Contents (% dry BV) | Major characteristics |
| | Peptides | | | | | Melittin | 2840 | 40–50 | 26 amino acid | | Enhance of PLA2 activity | | Cytotoxic effects against cancer cells | | Anti-inflammatory and antiarthritic effects | | Apamin | 2036 | 2–3 | 10 amino acid | | Inhibition of Ca2+ activated | | K+ channel | | Cytotoxic effect against cancer | | Nociceptive effect | | Anti-inflammatory properties | | MCD peptide | 2588 | 2–3 | 22 amino acid | | Anti-inflammatory and analgesic effect | | Histamine release (low dose) | | Histamine release inhibition (high dose) | | Antiallergic effect | | Adolapin | 11,500 | 1 | Inhibition of PLA2 and COX activity | | Anti-inflammatory activity | | Analgesic effect | | Protease inhibitor | 9000 | 0.8 | | | Minimine | 6000 | 2-3 | | | Procamine A,B | | 1.4 | | | Secarpin | | 0.5 | | | Tertiapin | | 0.1 | | | Melittin F | | 0.01 | | | Cardiopep | | 0.7 | |
| | Enzymes | | | | | PLA2 | 19,000 | 10–12 | Cytotoxic effects against cancer cells | | Inflammatory Effects | | Antitumor effects | | Hyaluronidase | 38,000 | 1.5–2 | Selectively attacks tissue hyaluronic acid polymers | | Increase the capillary permeability | | Immune response and tissue spread propertiesAntigenic | | Glucosidase | 170,000 | 0.6 | | | Acid phosphomonoesterase | 55,000 | 1 | |
| | Amines | | | | | Histamines | 307.14 | 1.5 | | | Dopamine | 189.64 | 0.13–1 | | | Norepinephrine | 169.18 | 0.1–0.7 | |
| | Others | | | | | Carbohydrates | 307.14 | 1.5 | | | r-Aminobutyric acid | 189.64 | 0.13–1 | | | B-Aminoisobutyric acid | 169.18 | 0.1–0.7 | |
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Source: Son et al. [84].
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