Self-Limiting OX513A Aedes aegypti Demonstrate Full Susceptibility to Currently Used Insecticidal Chemistries as Compared to Indian Wild-Type Aedes aegypti
Table 1
Mortalities and knockdown times (KDT) for male adults of OX513A (OX) and wild-type Aedes aegypti from Aurangabad (AWD) and Delhi (DEL) against diagnostic concentrations of four synthetic insecticides.
Insecticide (% conc)
Strain
Mortality 24 h (%) Mean ± SE
KDT in minutes (95% CI)
Regression line
Pearson chi-square test
value
Susceptibility status
KDT10
KDT50
KDT99
(df)
DDT 4%
OX (89)
90.9 ± 1.8
17.6 (13.3–21.1)
41.3 (37.2–46.8)
194.0 (136.0–351.3)
0.90
25.6 (10)
0.004
Resistance likely
AWD (80)
87.4 ± 5.4
34.7 (32.0–36.9)
57.5 (54.4–61.9)
143.5 (119.1–188.2)
0.86
3.7 (10)
0.961
Resistant
DEL (85)
44.4 ± 12.8
55.6
320.2
7681.2
0.18
102.1 (10)
<0.0001
Resistant
Malathion 5%
OX (92)
100.0 ± 0
22.7 (20.5–24.5)
33.6 (32.0–35.3)
68.9 (62.4–78.6)
0.95
16.1 (10)
0.098
Susceptible
AWD (92)
100.0 ± 0
26.4 (18.7–30.8)
38.1 (34.3–42.2)
59.3 (52.7–72.7)
0.88
109.0 (10)
<0.0001
Susceptible
DEL (89)
100.0 ± 0
25.5 (20.9–28.8)
41.3 (38.1–44.9)
99.2 (80.9–140.0)
0.92
34.5 (10)
<0.0001
Susceptible
Deltamethrin 0.05%
OX (99)
100.0 ± 0
5.9 (4.7–6.9)
8.7 (7.6–9.6)
17.2 (14.8–22.1)
0.34
21.7 (10)
<0.017
Susceptible
AWD (97)
100.0 ± 0
6.2 (5.4–6.8)
8.6 (8.0–9.1)
15.5 (14.1–17.7)
0.33
2.6 (10)
0.989
Susceptible
DEL (100)
100.0 ± 0
9.6 (5.6–12.2)
14.8 (11.4–17.5)
32.6 (25.7–56.1)
0.58
95.7 (10)
<0.0001
Susceptible
Permethrin 0.75%
OX (100)
100.0 ± 0
9.9 (8.1–11.0)
12.5 (11.3–13.7)
19.1 (16.7–25.1)
0.42
31.9 (10)
<0.0001
Susceptible
AWD (89)
100.0 ± 0
7.6 (5.4–9.2)
12.0 (10.2–13.7)
27.9 (23.0–38.8)
0.50
35.8 (10)
<0.0001
Susceptible
DEL (96)
100.0 ± 0
7.9 (4.8–10.4)
15.4 (12.1–18.2)
51.5 (39.1–84.6)
0.80
69.3 (10)
<0.0001
Susceptible
Differences in mean values indicated by the same letters within rows are nonsignificant at the 0.05 level by one-way ANOVA using Tukey’s -test; CI not calculable.
