Research Article

Self-Limiting OX513A Aedes aegypti Demonstrate Full Susceptibility to Currently Used Insecticidal Chemistries as Compared to Indian Wild-Type Aedes aegypti

Table 2

Mortalities and knockdown times (KDT) for female adults of OX513A (OX) and wild-type Aedes aegypti from Aurangabad (AWD) and Delhi (DEL) against diagnostic concentrations of four synthetic insecticides.

Insecticide (% conc)Strain Mortality 24 h (%) 
Mean ± SE
KDT in minutes (95% CI)Regression linePearson chi-square test valueSusceptibility status
KDT10KDT50KDT99 (df)

DDT 4%OX (97)70.1 ± 5.232.5
(28.2–35.6)
50.0
(46.9–54.2)
109.3
(89.8–153.3)
0.8626.6 (10)0.003Resistant
AWD (99)3.0 ± 2.0--------------Resistant
DEL (100)6.0 ± 7.782.0158.0518.70.2322.3 (10)0.014Resistant


Malathion 5%OX (98)100.0 ± 033.0
(27.9–36.4)
45.3
(42.2–48.7)
80.2
(68.7–107.6)
0.8050.8 (10)<0.0001Susceptible
AWD (98)100.0 ± 036.2
(24.1–41.9)
58.5
(50.8–84.3)
139.3
(92.1–640.1)
0.5779.4 (10)<0.0001Susceptible
DEL (99)98.0 ± 1.242.2
(30.5–51.0)
92.9
(68.0–362.8)
390.0
(165.6–22565.6)
0.6044.2 (10)<0.0001 Susceptible


Deltamethrin 0.05%OX (99)100.0 ± 08.1
(7.3–8.9)
12.0
(11.3–12.6)
24.3
(22.2–27.5)
0.526.0 (10)0.813Susceptible
AWD (98)100.0 ± 011.7
(10.8–12.4)
15.1
(14.5–15.7)
23.8
(22.2–26.2)
0.596.3 (10)0.792Susceptible
DEL (100)100.0 ± 010.5
(8.0–12.4)
16.7
(14.6–18.5)
38.7
(32.6–51.3)
0.7139.7 (10)<0.0001Susceptible

Permethrin 0.75%OX (89)100.0 ± 09.3
(8.5–9.9)
12.2
(11.6–12.7)
20.0
(18.4–22.5)
0.501.5 (10)0.999Susceptible
AWD (89)100.0 ± 08.7
(6.1–10.9)
15.3
(12.8–17.6)
42.7
(34.7–60.1)
0.6444.9 (10)<0.0001Susceptible
DEL (100)100.0 ± 014.0
(12.5–15.2)
20.5
(19.3–21.6)
41.0
(37.1–46.8)
0.8215.3 (10)0.123Susceptible

Differences in mean values indicated by the same letters within rows are nonsignificant at the 0.05 level by one-way ANOVA using Tukey’s -test; CI not calculable; --knockdown rates were insufficient to calculate.