Self-Limiting OX513A Aedes aegypti Demonstrate Full Susceptibility to Currently Used Insecticidal Chemistries as Compared to Indian Wild-Type Aedes aegypti
Table 2
Mortalities and knockdown times (KDT) for female adults of OX513A (OX) and wild-type Aedes aegypti from Aurangabad (AWD) and Delhi (DEL) against diagnostic concentrations of four synthetic insecticides.
Insecticide (% conc)
Strain
Mortality 24 h (%) Mean ± SE
KDT in minutes (95% CI)
Regression line
Pearson chi-square test
value
Susceptibility status
KDT10
KDT50
KDT99
(df)
DDT 4%
OX (97)
70.1 ± 5.2
32.5 (28.2–35.6)
50.0 (46.9–54.2)
109.3 (89.8–153.3)
0.86
26.6 (10)
0.003
Resistant
AWD (99)
3.0 ± 2.0
--
--
--
--
--
--
--
Resistant
DEL (100)
6.0 ± 7.7
82.0
158.0
518.7
0.23
22.3 (10)
0.014
Resistant
Malathion 5%
OX (98)
100.0 ± 0
33.0 (27.9–36.4)
45.3 (42.2–48.7)
80.2 (68.7–107.6)
0.80
50.8 (10)
<0.0001
Susceptible
AWD (98)
100.0 ± 0
36.2 (24.1–41.9)
58.5 (50.8–84.3)
139.3 (92.1–640.1)
0.57
79.4 (10)
<0.0001
Susceptible
DEL (99)
98.0 ± 1.2
42.2 (30.5–51.0)
92.9 (68.0–362.8)
390.0 (165.6–22565.6)
0.60
44.2 (10)
<0.0001
Susceptible
Deltamethrin 0.05%
OX (99)
100.0 ± 0
8.1 (7.3–8.9)
12.0 (11.3–12.6)
24.3 (22.2–27.5)
0.52
6.0 (10)
0.813
Susceptible
AWD (98)
100.0 ± 0
11.7 (10.8–12.4)
15.1 (14.5–15.7)
23.8 (22.2–26.2)
0.59
6.3 (10)
0.792
Susceptible
DEL (100)
100.0 ± 0
10.5 (8.0–12.4)
16.7 (14.6–18.5)
38.7 (32.6–51.3)
0.71
39.7 (10)
<0.0001
Susceptible
Permethrin 0.75%
OX (89)
100.0 ± 0
9.3 (8.5–9.9)
12.2 (11.6–12.7)
20.0 (18.4–22.5)
0.50
1.5 (10)
0.999
Susceptible
AWD (89)
100.0 ± 0
8.7 (6.1–10.9)
15.3 (12.8–17.6)
42.7 (34.7–60.1)
0.64
44.9 (10)
<0.0001
Susceptible
DEL (100)
100.0 ± 0
14.0 (12.5–15.2)
20.5 (19.3–21.6)
41.0 (37.1–46.8)
0.82
15.3 (10)
0.123
Susceptible
Differences in mean values indicated by the same letters within rows are nonsignificant at the 0.05 level by one-way ANOVA using Tukey’s -test; CI not calculable; --knockdown rates were insufficient to calculate.