Impact of Substance Use Disorder on Presentation and Short-Term Course of Schizophrenia

Table 4

PANSS, Calgary scale for depression, HARS, and BPRS scores at 6 weeks in schizophrenia patients with substance use disorder (Group 1) and without substance use disorder (Group 2).

	Variables	Group 1 (𝑛=91) Mean ± s.d.	Group 2 (𝑛=52) Mean ± s.d.	𝑡	Sig	CI Lower bound	CI Upper bound
PANSS	Positive scale	13.09±5.84	13.23±5.86	−0.130	0.897	−2.143	1.879
	Negative scale	16.10±7.63	14.98±6.96	0.878	0.382	−1.413	3.672
	Negative scale; Difficulty in abstraction	3.26±1.59	2.67±1.65	2.100	0.038	0.03	1.146
	General scale	25.84±6.72	26.61±7.63	−0.626	0.532	−3.198	1.659
HARS	Total score	6.23±6.89	4.84±5.01	1.269	0.207	−0.773	3.548
BPRS	Total score	12.45±9.11	12.17±8.95	0.176	0.860	−2.835	3.390
	Mannerism/posturing	0.23±0.45	0.35±0.48	−1.441	0.152	−0.27	−0.42
Calgary scale for depression	Depression	0.50±0.77	0.28±0.63	1.707	0.090	−0.03	0.468
	Self-depreciation	0.29±0.67	0.09±0.35	1.987	0.049	0.001	0.400
	Early waking	0.24±0.63	0.03±0.19	2.235	0.027	0.02	0.383
	Total score	2.24±4.58	0.98±2.53	1.827	0.070	−0.103	2.625

CI: confidence interval; “𝑡”: 𝑡 statistic; degree of freedom = 141.