The Potential Utility of Pharmacogenetic Testing in Psychiatry

Table 1

Cost effectiveness of genetic testing.

Study reference number	Gene(s)	Total number of study subjects	Average cost/resource use
[17–19]	CYP2D6 (extreme metabolism)	353	Testing reduces costs by 28%; PM have longer hospital stays; PM or UM have $4,000–6,000 higher costs
[17]	CYP2C19 (extreme metabolism)	104	Testing reduces costs by 28%
[20]	CYP2D6, CYP2C19, SLC6A4, CYP2C9, CYP1A2, and 5HTR2A	91	Patient with risks had 69% more healthcare visits, 67% more general medical visits, 3-fold more medical absence days, and 4-fold more disability claims
[21]	The Genecept Assay	333	Testing reduces outpatient costs by 9.5% or $562 over 4 months