|
| Modality of psychotherapy | Diagnosis | Study | Number of patients (intervention group) | Design | Treatment effects of psychotherapy |
|
| Eye movement desensitization and reprocessing (EMDR) | PTSD | Bossini et al. (2011) | 9 (unmedicated) | MRI
12 weeks (weekly 90-minute sessions) | Bilateral volume increase in the hippocampus |
| Pagani et al. (2007) | 15 (unmedicated) | SPECT
8 weeks (five 90-minute sessions) | Decreased tracer uptake in medial temporal cortex (uncus), hippocampus, occipitotemporal cortex, and visual cortex (BA 17) |
|
| Prolonged exposure (PE) | PTSD | Felmingham et al. (2007) | 8
(2 on SSRIs; the rest unmedicated) | fMRI
8 weeks of treatment (cognitive restructuring with imaginal exposure) | Increase in rACC activity and a decrease in bilateral amygdala activity |
| Helpman et al. (2016) | 16
(unmedicated) | fMRI
10-week PE protocol | Decrease in rACC activation and increased activity in the mPFC |
|
| Brief eclectic psychotherapy (BEP) | PTSD | Lindauer et al. (2008) | 20
(unmedicated) | SPECT
16 weekly sessions | Decrease in rCBF in the right uncus
Increase in rCBF in the left superior temporal gyrus |
|
| Guided imagery | MDD | Huang et al. (2014) | 23 (unmedicated) | fMRI
5 weeks of treatment | Increase in regional homogeneity in the vmPFC and ACC |
|
| Interpersonal psychotherapy (IPT) | MDD | Brody et al. (2001)
[145] | 39
(unmedicated) | PET
12 weeks of CBT
(comparison group received paroxetine) | Increased activity in the dlPFC and dACC
Decrease in activity in the vACC and anterior insula |
Brody et al. (2001)
[146] | 24
(unmedicated) | PET
12 weeks of IPT
Comparison group received paroxetine | Reduced activity in lateral PFC, caudate, thalamus, left ACC Increased activity in left temporal lobe
|
| Martin et al. (2011) | 10 (unmedicated) | SPECT
Up to 16 hour-long weekly sessions
(comparison group was treated with venlafaxine) | Increased blood flow in right BG and right PCC |
|
| Dialectical behavioral therapy (DBT) | BPD | Goodman et al. (2014) | 11
(unmedicated) | fMRI
12 months of DBT | Decrease in amygdala activation to unpleasant images |
| Paret et al. (2016) | 8
(all patients on medications) | fMRI
12 weeks of DBT; amygdala neurofeedback (NF) incorporated for 4 sessions | Increased connectivity between vmPFC and amygdala (did not persist without NF component) |
|
