Self-Reported Adverse Drug Reactions, Medication Adherence, and Clinical Outcomes among Major Depressive Disorder Patients in Ethiopia: A Prospective Hospital Based Study
Table 3
Factors associated with medication adherence.
Variable
Level of adherence
Crude OR
Adjusted OR
Optimal
Suboptimal
Sex
Male
55 (25.34)
67 (30.88)
1
1
Female
38 (17.51)
57 (26.26)
1.231
1.103
Residence
Urban
72 (33.18)
53 (24.42)
1
1
Rural
21 (9.68)
71 (42.72)
4.593
2.008
Disease duration
Less than two years
51 (23.03)
41 (18.89)
1
1
More than two years
42 (19.35)
83 (9.68)
2.458
2.424
Distance
<2 hours
82 (37.78)
71 (32.72)
1
1
≥2 hours
11 (5.10)
53 (24.42)
5.565
5.061
Other psychiatric illness
Yes
40 (18.43)
85 (39.17)
1
1
No
53 (24.42)
39 (17.97)
2.888
2.228
Naranjo score
Possible
12 (5.53%)
7 (3.22%)
1
1
Probable
56 (28.80%)
112 (51.61%)
3.429
2.838
Severity of ADR
Moderate
59 (27.18%)
91 (41.93)
1
1
Sever
8 (3.69%)
28 (12.90)
2.269
1.172
Statistically significant at 0.05. Significant at 0.01.
