Treatment of Fatigue in Multiple Sclerosis Patients: A Neurocognitive Approach

Table 1

Mean clinical variable scores at baseline and after five weeks of treatment (𝑛=20).

Variable	Baseline mean (SD)	First follow-up mean (SD)	𝑃
EDSS	2.45 (1.29)	2.48 (1.26)	N.S.
FSS	5.66 (0.48)	4.20 (1.07)	<0.0001
MFIS	36.50 (14.28)	23.80 (12.40)	<0.0001
pMFIS	20.15 (6.33)	13.45 (6.68)	<0.0001
cMFIS	14.15 (8.36)	8.55 (6.16)	<0.0001
psMFIS	2.20 (2.12)	1.70 (1.53)	0.133
MSFC	0.10 (0.61)	0.21 (0.56)	0.035
NHPT	22.04 (5.73)	21.04 (4.34)	0.083
25FWT	5.83 (1.78)	5.58 (1.94)	0.093
PASAT	39.55 (12.09)	41.65 (13.19)	0.095
MSQOL-54
PHCS	52.46 (17.08)	65.17 (15.98)	0.002
MHCS	60.78 (16.80)	70.48 (16.33)	0.004

EDDS: Expanded Disability Status Scale, MSFC: Multiple Sclerosis Functional Composite, NHPT: Nine-Hole Peg Test, 25 FWT: 25-Foot Walking Test, PASAT: Paced Auditory Serial Addition Test, FSS: Fatigue Severity Scale, MFIS: Modified Fatigue Impact Scale, pMFIS: physical MFIS subscale, cMFIS: cognitive MFIS subscale, psMFIS: psychosocial MFIS subscale, MSQOL-54: Multiple Sclerosis Quality of Life Questionnaire, PHCS: Physical Health Composite Score, MHCS: Mental Health Composite Score.