Review Article
Chronic Traumatic Encephalopathy: A Review
Table 2
Areas of damage in the brain.
| Gross areas of damage | | (i) Reduced brain weight with atrophy of | | Frontal lobe | | Temporal lobe | | Parietal lobe | | Occipital lobe | | (ii) Enlargement of lateral and third ventricles | | (iii) Thinning of the corpus callosum | | (iv) Cavum septum pellucidum with fenestrations | | (v) Scarring and neuronal loss of cerebellar tonsils | | (vi) Pallor of substantia nigra | |
| Areas of tau NFTs and NT | | (i) Superficial cortical layers | | (ii) Dorsolateral frontal | | (iii) Subcallosal | | (iv) Insular | | (v) Temporal | | (vi) Dorsolateral parietal | | (vii) Inferior occipital cortices | | (viii) Thalamus | | (ix) Hypothalamus | | (x) Substantia nigra | | (xi) Olfactory bulbs | | (xii) Hippocampus | | (xiii) Entorhinal cortex | | (xiv) Amygdala | | (xv) Brainstem | |
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