Emerging histomorphologic phenotypes in American athletes.
Phenotype
Histological findings
1
Sparse to frequent NFT and NTs in the cerebral cortex and brainstem without involvement of the subcortical nuclei, basal ganglia, or cerebellum without any beta-amyloid
2
Sparse to frequent NFT and NTs in the cerebral cortex and brainstem with diffuse beta-amyloid deposition. No involvement of the subcortical nuclei, basal ganglia, or cerebellum
3
Higher concentrations of NFTs and NTs only in the brainstem. No involvement elsewhere or any beta-amyloid
4
Sparse NFTs and NTs in the cerebral cortex, brainstem, subcortical nuclei, and basal ganglia with an unaffected cerebellum and no beta-amyloid [18]
