Clinical Study

The Severity of Fatty Liver Disease Relating to Metabolic Abnormalities Independently Predicts Coronary Calcification

Table 1

Baseline demographic data and clinical information in our study.

 Calcium score zero ( 𝑁 = 2 3 9 )Calcium score abnormal ( 𝑁 = 1 0 3 ) 𝑃 value

Age, years47.0 (6.4)52.6 (6.6)<0.001
Gender, female %66 (27.6)11 (10.6)
Height, cm165.9 (7.5)167.7 (7.5)0.09
Weight, kg65.9 (11.3)68.9 (10.1)0.008
BMI, Kg/m223.8 (3.1)24.4 (2.7)0.013
Waist, cm81.4 (9.1)85.0 (7.9)<0.001
Waist to hip ratio0.88 (0.07)0.91 (0.06)<0.001
SBP, mmHg116.7 (14.9)125.1 (15.1)0.003
DBP, mmHg74.5 (10.2)77.9 (9.7)0.002
Biochemistry
 Sugar (AC), mg/dL93.3 (21.2)102.0 (20.9)0.086
 Sugar (PC), mg/dL105.9 (31.6)118.5 (44.4)0.082
 HbA1c, %5.8 (0.6)6.0 (0.6)0.32
 Insulin, U/mL6.25 (4.24)6.91 (3.75)0.046
 HOMA-IR1.55 (1.25)1.76 (1.06)0.016
 Cholesterol, mg/dL191.1 (32.9)196.1 (35.1)0.23
 LDL, mg/dL128.0 (31.3)125.8 (31.7)0.56
 HDL, mg/dL53.0 (13.7)49.1 (12.8)0.02
 TG, mg/dL141.9 (103)145.8 (85.2)0.74
 BUN, mg/dL11.8 (3.2)12.6 (3.7)0.32
 Creatinine, mg/dL0.91 (0.18)0.97 (0.18)0.39
 Uric Acid, mg/dL5.6 (1.4)6.1 (1.5)0.003
 Homocystine, mg/dL7.3 (2.1)8.4 (2.3)0.03
 Hs-CRP, mg/dL0.2 (0.35)0.32 (0.7)0.043
ECG pattern
 ECG (LVH or myocardial ischemia)41 (7.5)28 (13.2)0.016
 ECG (old infarct)5 (1)9 (4.2)0.002
Medical history
 Smoking84 (24.9)42 (29.4)0.311
 HTN history41 (12)35 (23.7)0.001
 DM history11 (3.2)14 (9.5)0.004
 Hyperlipidemia17 (5.6)13 (9.6)0.039
 CVD12 (3.9)12 (8.9)0.033
Family Hx
 Family Hx HTN147 (43)62 (41.9)0.823
 Family Hx DM88 (25.8)42 (28.4)0.554
 Family Hx Stroke49 (14.3)20 (13.5)0.812
 Family Hx CVD57 (16.7)30 (20.3)0.345

BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; sugar (AC): fasting glucose; sugar (PC): postprandial glucose; HOMA-IR: insulin resistance; ECG: electrocardiography; LVH: left ventricular hypertrophy; HTN: hypertension; DM: diabetes; NAFLD: nonalcoholic fatty liver disease; CVD: cardiovascular disease: Hx: history.